Study of Disaccharide Conformation by One - and Two - Dimensional NMR Spectroscopy : 1 , 6 - Anhydro - / 3 - maltose Hexaacetate
نویسنده
چکیده
Oneand two-dimensional NMR spectroscopy were employed to determine the conformation of 2,3,4,6,2',3'-hexaO-acetyl-4-O-a-D-glucopyranosyl-1',6'-anhydro-~-D-glucop~anose in acetone-d, solution. Inter-residue interproton distances, H-1-H-4' and H-1-H-Q', determined by 2D NOE experiments are commensurate with torsional angles + and $ of 10" and -20", and also of 10" and -No, about the inter-residue glucosidic bond. Computer simulation showed that, within the limits of the experimental error (ca f0.20 di) of the interproton distances determined, several sets of + and $ angles are consistent with the NMR data. These 'allowed' conformations are presented in the form of a conformational map.
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